A Unique Model System for Tumor Progression in GBM Comprising Two Developed Human Neuro-Epithelial Cell Lines with Differential Transforming Potential and Coexpressing Neuronal and Glial Markers

A Unique Model System for Tumor Progression in GBM Comprising Two Developed Human Neuro-Epithelial Cell Lines with Differential Transforming Potential and Coexpressing Neuronal and Glial Markers

The molecular mechanisms involved in tumor progression from a low-grade astrocytoma to the most malignant glioblastoma multiforme (GBM) have been hampered due to lack of suitable experimental models. We have established a model of tumor progression comprising of two cell lines derived from the same...

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Bibliographic Details
Main Authors: Anjali Shiras, Arti Bhosale, Varsha Shepal, Ravi Shukla, V.S. Baburao, K. Prabhakara, Padma Shastry
Format: Article
Language:English
Published: Elsevier 2003-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Glioblastoma
tumorigenicity
invasion
c-erbB2
neuroglial
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558603800362

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http://www.sciencedirect.com/science/article/pii/S1476558603800362

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