Harnessing allogeneic NK cells: improving outcomes with tailored donor lymphocyte infusion
Since researchers first began to uncover the mechanisms underlying allogeneic transplantation, the focus has been on T cells. T cells are a major instigator of graft-versus-host disease (GVHD). The clear association between GVHD occurrence and subsequent reduction in relapse supported concentrating...
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-06-01
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Series: | The Journal of Clinical Investigation |
Online Access: | https://doi.org/10.1172/JCI160584 |