Harnessing allogeneic NK cells: improving outcomes with tailored donor lymphocyte infusion

Since researchers first began to uncover the mechanisms underlying allogeneic transplantation, the focus has been on T cells. T cells are a major instigator of graft-versus-host disease (GVHD). The clear association between GVHD occurrence and subsequent reduction in relapse supported concentrating...

Full description

Bibliographic Details
Main Author: Shannon R. McCurdy
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-06-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI160584