Activation of Adrenoceptor Alpha-2 (ADRA2A) Promotes Chemosensitization to Carboplatin in Ovarian Cancer Cell Lines

Activation of Adrenoceptor Alpha-2 (ADRA2A) Promotes Chemosensitization to Carboplatin in Ovarian Cancer Cell Lines

Recurrence of ovarian cancer (OvCa) following surgery and standard carboplatin/paclitaxel first-line therapy signifies poor median progression-free survival (<24 months) in the majority of patients with OvCa. The current study utilized unbiased high-throughput screening (HTS) to evaluate an FDA-a...

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Bibliographic Details
Main Authors: Haya Albanna, Alesia Gjoni, Danielle Robinette, Gerardo Rodriguez, Lora Djambov, Margaret E. Olson, Peter C. Hart
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Current Issues in Molecular Biology
Subjects:
ovarian cancer
OvCa
carboplatin resistance
ADRA2A
adrenoceptor alpha-2a
Online Access:https://www.mdpi.com/1467-3045/45/12/598

Internet

https://www.mdpi.com/1467-3045/45/12/598

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