Mice lacking GD3 synthase display morphological abnormalities in the sciatic nerve and neuronal disturbances during peripheral nerve regeneration.

Mice lacking GD3 synthase display morphological abnormalities in the sciatic nerve and neuronal disturbances during peripheral nerve regeneration.

The ganglioside 9-O-acetyl GD3 is overexpressed in peripheral nerves after lesioning, and its expression is correlated with axonal degeneration and regeneration in adult rodents. However, the biological roles of this ganglioside during the regenerative process are unclear. We used mice lacking GD3 s...

Full description

Bibliographic Details
Main Authors: Victor Túlio Ribeiro-Resende, Tiago Araújo Gomes, Silmara de Lima, Maiara Nascimento-Lima, Michele Bargas-Rega, Marcelo Felipe Santiago, Ricardo Augusto de Melo Reis, Fernando Garcia de Mello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199601?pdf=render

Internet

http://europepmc.org/articles/PMC4199601?pdf=render

Similar Items