Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition

Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition

Acute myeloid leukaemia (AML) affects predominantly elderly people and has an incidence of 1% of all cancers and 2% of all cancer deaths. Despite using intensive chemotherapy and allogeneic stem cell transplantation, the treatment options for AML remain open for innovation. Thus, there is a need to...

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Bibliographic Details
Main Authors: Saiful Islam, Muhammed H. Rahaman, Mingfeng Yu, Benjamin Noll, Jennifer H. Martin, Shudong Wang, Richard Head
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
repurposing
rilpivirine
targeted therapy
Aurora A kinase
cancer
leukaemia
Online Access:https://www.mdpi.com/2072-6694/15/4/1044

Internet

https://www.mdpi.com/2072-6694/15/4/1044

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