Regioselective Electrophilic Addition to Propargylic B(MIDA)s Enabled by β‐Boron Effect

Regioselective Electrophilic Addition to Propargylic B(MIDA)s Enabled by β‐Boron Effect

Abstract Electrophilic addition reaction to alkynes is of fundamental importance in organic chemistry, yet the regiocontrol when reacting with unsymmetrical 1,2‐dialkyl substituted alkynes is often problematic. Herein, it is demonstrated that the rarely recognized β‐boron effect can confer a high le...

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Bibliographic Details
Main Authors: Yin Li, Zhi‐Hao Chen, Shuang Lin, Yuan Liu, Jiasheng Qian, Qingjiang Li, Zhi‐Shu Huang, Honggen Wang
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Advanced Science
Subjects:
electrophilic addition
hydration
internal alkyne
β‐boron effect
β‐difluoroalkylboron
Online Access:https://doi.org/10.1002/advs.202304282

Internet

https://doi.org/10.1002/advs.202304282

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