Development and Characterization of PEGylated Fatty Acid-<i>Block</i>-Poly(ε-caprolactone) Novel Block Copolymers and Their Self-Assembled Nanostructures for Ocular Delivery of Cyclosporine A

Development and Characterization of PEGylated Fatty Acid-<i>Block</i>-Poly(ε-caprolactone) Novel Block Copolymers and Their Self-Assembled Nanostructures for Ocular Delivery of Cyclosporine A

Low aqueous solubility and membrane permeability of some drugs are considered major limitations for their use in clinical practice. Polymeric micelles are one of the potential nano-drug delivery systems that were found to ameliorate the low aqueous solubility of hydrophobic drugs. The main objective...

Full description

Bibliographic Details
Main Authors: Ziyad Binkhathlan, Abdullah H. Alomrani, Olsi Hoxha, Raisuddin Ali, Mohd Abul Kalam, Aws Alshamsan
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Polymers
Subjects:
cyclosporine A
ethoxylated fatty acid
block copolymer
polymeric micelles
ocular
Online Access:https://www.mdpi.com/2073-4360/14/9/1635

Internet

https://www.mdpi.com/2073-4360/14/9/1635

Similar Items