Toll-Like Receptor 4: A Macrophage Cell Surface Receptor Is Activated by Trimethylamine-N-Oxide

Objective: Trimethylamine-N-Oxide (TMAO) is considered as a risk factor for atherosclerosis which further leads to inflammation during atherosclerosis. The exact mechanism(s) by which TMAO induces the inflammatory reactions remains to be determined. TMAO can cause the endoplasmic reticulum (ER) stre...

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Bibliographic Details
Main Authors: Mohammad Saeed Hakhamaneshi, Alina Abdolahi, Zakaria Vahabzadeh, Mohammad Abdi, Pedram Andalibi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2021-10-01
Series:Cell Journal
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Online Access:https://celljournal.org/journal/article/fulltext/toll-like-receptor-4-a-macrophage-cell-surface-receptor-is-activated-by-trimethylamine-n-oxide-during-atherosclerosis.pdf