Synthesis and cytotoxicity of apoptosis-inducing N-heterocyclic triterpene amides
The modification of lipophilic triterpenes to enhance their cytotoxicity, is a viable strategy for finding new anti-cancer agents. Herein we report the synthesis, analysis of 18 pentacyclic triterpenoic acid N-heterocyclic amides and their cytotoxicity, tumor cell/non-tumor cell selectivity, as well...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-12-01
|
| Series: | European Journal of Medicinal Chemistry Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417422000577 |