Cytotoxic Activity and Antiproliferative Effects of Crude Skin Secretion from Physalaemus nattereri (Anura: Leptodactylidae) on in vitro Melanoma Cells

Cytotoxic Activity and Antiproliferative Effects of Crude Skin Secretion from Physalaemus nattereri (Anura: Leptodactylidae) on in vitro Melanoma Cells

Anuran secretions are rich sources of bioactive molecules, including antimicrobial and antitumoral compounds. The aims of this study were to investigate the therapeutic potential of Physalaemus nattereri skin secretion against skin cancer cells, and to assess its cytotoxic action mechanisms on the m...

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Bibliographic Details
Main Authors: Andréa Cruz e Carvalho, César Augusto Prías Márquez, Ricardo Bentes Azevedo, Graziella Anselmo Joanitti, Osmindo Rodrigues Pires Júnior, Wagner Fontes, Mariana S. Castro
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Toxins
Subjects:
anurans
antitumoral activity
Physalaemus nattereri
skin secretion
melanoma
cytotoxicity
Online Access:http://www.mdpi.com/2072-6651/7/10/3989

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http://www.mdpi.com/2072-6651/7/10/3989

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