AKT and MAPK signaling pathways in hippocampus reveals the pathogenesis of depression in four stress-induced models

Abstract Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The pathogenesis of MDD remained unclear, and it may be associated with exposure to different stressors. Most previous studies have focused on molecular changes in a single stress-induced depression model, which...

Full description

Bibliographic Details
Main Authors: Xuemei Li, Teng Teng, Wei Yan, Li Fan, Xueer Liu, Gerard Clarke, Dan Zhu, Yuanliang Jiang, Yajie Xiang, Ying Yu, Yuqing Zhang, Bangmin Yin, Lin Lu, Xinyu Zhou, Peng Xie
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02486-3