The additive interaction of healthy lifestyles and genetic susceptibility on colorectal cancer risk in prediabetes: a large population-based prospective cohort study

Abstract Objective We aimed to investigate the interrelationships among polygenic risk scores (PRS), healthy lifestyle factors (HLFs), and colorectal cancer (CRC) risk in individuals with prediabetes. To investigate whether adherence to HLFs influence CRC risk in those with elevated PRS within this...

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Bibliographic Details
Main Authors: Wenchen Wang, Yikang Cheng, Qingyu Meng, Baoqing Jia, Dawei Yao, Yiping Cheng
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-024-03552-w