Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA.

Cell migration is of paramount importance to organism development and maintenance as well as multiple pathological processes, including cancer metastasis. The RhoGTPases Rac1 and RhoA are indispensable for cell migration as they regulate cell protrusion, cell-extracellular matrix (ECM) interactions...

Full description

Bibliographic Details
Main Authors: Nicholas O Deakin, Christoph Ballestrem, Christopher E Turner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3358283?pdf=render