Assessing structure and disorder prediction tools for de novo emerged proteins in the age of machine learning [version 1; peer review: 2 approved]
Background: De novo protein coding genes emerge from scratch in the non-coding regions of the genome and have, per definition, no homology to other genes. Therefore, their encoded de novo proteins belong to the so-called "dark protein space". So far, only four de novo protein structures ha...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2023-03-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/12-347/v1 |