Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex

Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex

Mitochondrial Ca2+ uptake, a process crucial for bioenergetics and Ca2+ signaling, is catalyzed by the mitochondrial calcium uniporter. The uniporter is a multi-subunit Ca2+-activated Ca2+ channel, with the Ca2+ pore formed by the MCU protein and Ca2+-dependent activation mediated by MICU subunits....

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Bibliographic Details
Main Authors: Ming-Feng Tsai, Charles B Phillips, Matthew Ranaghan, Chen-Wei Tsai, Yujiao Wu, Carole Williams, Christopher Miller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
calcium transport
MCU
EMRE
ion channel
mitochondria
Online Access:https://elifesciences.org/articles/15545

Internet

https://elifesciences.org/articles/15545

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