Estradiol cycling drives female obesogenic adipocyte hyperplasia

Summary: White adipose tissue (WAT) distribution is sex dependent. Adipocyte hyperplasia contributes to WAT distribution in mice driven by cues in the tissue microenvironment, with females displaying hyperplasia in subcutaneous and visceral WAT, while males and ovariectomized females have visceral W...

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Bibliographic Details
Main Authors: Rocío del M. Saavedra-Peña, Natalia Taylor, Clare Flannery, Matthew S. Rodeheffer
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723004011