Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms

Scientific Opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) effect models for regulatory risk assessment of pesticides for aquatic organisms

Abstract Following a request from EFSA, the Panel on Plant Protection Products and their Residues (PPR) developed an opinion on the state of the art of Toxicokinetic/Toxicodynamic (TKTD) models and their use in prospective environmental risk assessment (ERA) for pesticides and aquatic organisms. TKT...

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Bibliographic Details
Main Authors: EFSA Panel on Plant Protection Products and their Residues (PPR), Colin Ockleford, Paulien Adriaanse, Philippe Berny, Theodorus Brock, Sabine Duquesne, Sandro Grilli, Antonio F Hernandez‐Jerez, Susanne Hougaard Bennekou, Michael Klein, Thomas Kuhl, Ryszard Laskowski, Kyriaki Machera, Olavi Pelkonen, Silvia Pieper, Robert H Smith, Michael Stemmer, Ingvar Sundh, Aaldrik Tiktak, Christopher J. Topping, Gerrit Wolterink, Nina Cedergreen, Sandrine Charles, Andreas Focks, Melissa Reed, Maria Arena, Alessio Ippolito, Harry Byers, Ivana Teodorovic
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:EFSA Journal
Subjects:
Toxicokinetic/Toxicodynamic models
aquatic organisms
prospective risk assessment
time‐variable exposure
model calibration
model validation
Online Access:https://doi.org/10.2903/j.efsa.2018.5377

Internet

https://doi.org/10.2903/j.efsa.2018.5377

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