Influenza Vaccine With Consensus Internal Antigens as Immunogens Provides Cross-Group Protection Against Influenza A Viruses

Influenza Vaccine With Consensus Internal Antigens as Immunogens Provides Cross-Group Protection Against Influenza A Viruses

Given that continuing antigenic shift and drift of influenza A viruses result in the escape from previous vaccine-induced immune protection, a universal influenza vaccine has been actively sought. However, there were very few vaccines capable of eliciting cross-group ant-influenza immunity. Here, we...

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Bibliographic Details
Main Authors: Xinci Xie, Chen Zhao, Qian He, Tianyi Qiu, Songhua Yuan, Longfei Ding, Lu Liu, Lang Jiang, Jing Wang, Linxia Zhang, Chao Zhang, Xiang Wang, Dongming Zhou, Xiaoyan Zhang, Jianqing Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
universal influenza vaccine
consensus sequence
CD8+ T cell epitope
cross-protection
lung residential T cells
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01630/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01630/full

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