Changing Perspectives on the Role of DnaA-ATP in Orisome Function and Timing Regulation

Bacteria, like all cells, must precisely duplicate their genomes before they divide. Regulation of this critical process focuses on forming a pre-replicative nucleoprotein complex, termed the orisome. Orisomes perform two essential mechanical tasks that configure the unique chromosomal replication o...

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Bibliographic Details
Main Authors: Alan C. Leonard, Prassanna Rao, Rohit P. Kadam, Julia E. Grimwade
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02009/full