Functional characterization of cannabidiol effect on the serotonergic neurons of the dorsal raphe nucleus in rat brain slices

Functional characterization of cannabidiol effect on the serotonergic neurons of the dorsal raphe nucleus in rat brain slices

Cannabidiol (CBD), the main non-psychoactive cannabinoid found in the cannabis plant, elicits several pharmacological effects via the 5-HT1A receptor. The dorsal raphe nucleus (DRN) is the main serotonergic cluster in the brain that expresses the 5-HT1A receptor. To date, the effect of CBD on the ne...

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Bibliographic Details
Main Authors: Aitziber Mendiguren, Erik Aostri, Elena Alberdi, Alberto Pérez-Samartín, Joseba Pineda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
cannabidiol
5-HT1A receptor
dorsal raphe nucleus
slice
firing
rat
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.956886/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.956886/full

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