Tissue Engineering the Annulus Fibrosus Using 3D Rings of Electrospun PCL:PLLA Angle-Ply Nanofiber Sheets

Tissue Engineering the Annulus Fibrosus Using 3D Rings of Electrospun PCL:PLLA Angle-Ply Nanofiber Sheets

Treatments to alleviate chronic lower back pain, caused by intervertebral disc herniation as a consequence of degenerate annulus fibrosus (AF) tissue, fail to provide long-term relief and do not restore tissue structure or function. The future of AF tissue engineering relies on the production of its...

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Bibliographic Details
Main Authors: Alyah H. Shamsah, Sarah H. Cartmell, Stephen M. Richardson, Lucy A. Bosworth
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
electrospinning
annulus fibrosus
polycaprolactone
poly(L-lactic) acid
polymer blend
cell-sheet-rolling-system
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00437/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00437/full

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