Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study

Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study

LP-211 is a new, selective agonist of serotonin (5-hydroxytryptamine, 5-HT) receptor 7 (5-HT7-R), which is part of a neuro-transmission system with a proposed role in neural plasticity and in mood, cognitive or sleep regulation. Adolescent subchronic LP-211 treatment produces some persisting changes...

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Bibliographic Details
Main Authors: Luisa eAltabella, Marco eSbriccoli, Francesca eZoratto, Anna ePoleggi, Ramona eVinci, Enza eLacivita, Marcello eLeopoldo, Giovanni eLaviola, Franco eCardone, Rossella eCanese, Walter eAdriani
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Hippocampus
Nucleus Accumbens
septum
Limbic/Cortical loop
LP-211
Ph-MRI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00427/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00427/full

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