A novel GRN mutation in an Italian patient with non-fluent variant of primary progressive aphasia at onset: a longitudinal case report

A novel GRN mutation in an Italian patient with non-fluent variant of primary progressive aphasia at onset: a longitudinal case report

ObjectivesWe report the clinical presentation and evolution of a case with a novel Progranulin gene (GRN) mutation and non-fluent language disturbances at onset.Materials and methodsA 60 year-old, white patient was followed due to a history of language disturbances. Eighteen months after onset, the...

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Bibliographic Details
Main Authors: Veronica Castelnovo, Elisa Canu, Teuta Domi, Laura Pozzi, Francesca Vignaroli, Edoardo Gioele Spinelli, Alma Ghirelli, Giacomo Tondo, Cristoforo Comi, Nilo Riva, Angelo Quattrini, Paola Carrera, Massimo Filippi, Federica Agosta
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neuroscience
Subjects:
progranulin
primary progressive aphasia
longitudinal
frontotemporal dementia
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1204504/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1204504/full

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