Heparanase and Syndecan-4 Are Involved in Low Molecular Weight Fucoidan-Induced Angiogenesis

Heparanase and Syndecan-4 Are Involved in Low Molecular Weight Fucoidan-Induced Angiogenesis

Induction of angiogenesis is a potential treatment for chronic ischemia. Low molecular weight fucoidan (LMWF), the sulfated polysaccharide from brown seaweeds, has been shown to promote revascularization in a rat limb ischemia, increasing angiogenesis in vivo. We investigated the potential role of...

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Bibliographic Details
Main Authors: Oualid Haddad, Erwan Guyot, Nicolas Marinval, Fabien Chevalier, Loïc Maillard, Latifa Gadi, Christelle Laguillier-Morizot, Olivier Oudar, Angela Sutton, Nathalie Charnaux, Hanna Hlawaty
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Marine Drugs
Subjects:
fucoidan
angiogenesis
human endothelial cell
glycosaminoglycan
syndecan
heparanase
Online Access:http://www.mdpi.com/1660-3397/13/11/6588

Internet

http://www.mdpi.com/1660-3397/13/11/6588

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