Synthesis of Carbonyl-Containing Oxindoles via Ni-Catalyzed Reductive Aryl-Acylation and Aryl-Esterification of Alkenes

Synthesis of Carbonyl-Containing Oxindoles via Ni-Catalyzed Reductive Aryl-Acylation and Aryl-Esterification of Alkenes

Carbonyl-containing oxindoles are ubiquitous core structures present in many biologically active natural products and pharmaceutical molecules. Nickel-catalyzed reductive aryl-acylation of alkenes using aryl anhydrides or alkanoyl chlorides as acyl sources is developed, providing 3,3-disubstituted o...

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Bibliographic Details
Main Authors: Zhengtian Ding, Wangqing Kong
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
nickel catalysis
reductive coupling reaction
aryl-acylation
aryl-esterification
oxindoles
Online Access:https://www.mdpi.com/1420-3049/27/18/5899

Internet

https://www.mdpi.com/1420-3049/27/18/5899

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