Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice

Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice

Objectives: Schizophrenia (SCZ) patients display higher incidence of metabolic syndrome (MetS) and comorbidity of type II diabetes. Both atypical antipsychotics and genetic variants are believed to predispose the patients with the risk, but their interplay remains largely unknown. TCF7L2 is one of t...

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Bibliographic Details
Main Authors: Ye Yang, Manjun Shen, Li Li, Yujun Long, Lu Wang, Bing Lang, Renrong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TCF7L2
CKO
olanzapine
metabolic disorders
GLP-1R
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.890472/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.890472/full

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