SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules

SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules

Antiviral agents are needed for the treatment of SARS-CoV-2 infections and to control other coronavirus outbreaks that may occur in the future. Here we report the identification and characterization of RNA-binding compounds that inhibit SARS-CoV-2 replication. The compounds were detected by screenin...

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Bibliographic Details
Main Authors: Alvaro Simba-Lahuasi, Ángel Cantero-Camacho, Romel Rosales, Briana Lynn McGovern, M. Luis Rodríguez, Vicente Marchán, Kris M. White, Adolfo García-Sastre, José Gallego
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceuticals
Subjects:
antiviral drug
coronavirus
COVID-19
RNA
SARS-CoV-2
3’UTR S2m hairpin
Online Access:https://www.mdpi.com/1424-8247/15/12/1448

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https://www.mdpi.com/1424-8247/15/12/1448

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