Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement

Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement

Abstract Malaria parasite lacks canonical pathways for amino acid biosynthesis and depends primarily on hemoglobin degradation and extracellular resources for amino acids. Interestingly, a putative gene for glutamine synthetase (GS) is retained despite glutamine being an abundant amino acid in human...

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Bibliographic Details
Main Authors: Sourav Ghosh, Rajib Kundu, Manjunatha Chandana, Rahul Das, Aditya Anand, Subhashree Beura, Ruchir Chandrakant Bobde, Vishal Jain, Sowmya Ramakant Prabhu, Prativa Kumari Behera, Akshaya Kumar Mohanty, Mahabala Chakrapani, Kapaettu Satyamoorthy, Amol Ratnakar Suryawanshi, Anshuman Dixit, Govindarajan Padmanaban, Viswanathan Arun Nagaraj
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39670-4

Internet

https://doi.org/10.1038/s41467-023-39670-4

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