RORα inhibits gastric cancer proliferation through attenuating G6PD and PFKFB3 induced glycolytic activity

RORα inhibits gastric cancer proliferation through attenuating G6PD and PFKFB3 induced glycolytic activity

Abstract Background Glycolysis is critical for harvesting abundant energy to maintain the tumor microenvironment in malignant tumors. Retinoic acid-related orphan receptor α (RORα) has been identified as a circadian gene. However, the association of glycolysis with RORα in regulating gastric cancer...

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Bibliographic Details
Main Authors: Xiaoshan Wang, Junyi Zhang, Yuwei Wu, Yuqing Zhang, Siyuan Zhang, Angqing Li, Jian Wang, Zhengguang Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cancer Cell International
Subjects:
RORα
Proliferation
G6PD
PFKFB3
Glycolysis
Gastric cancer
Online Access:https://doi.org/10.1186/s12935-023-03201-4

Internet

https://doi.org/10.1186/s12935-023-03201-4

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