USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication

USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication

DNA replication control is a key process in maintaining genomic integrity. Monitoring DNA replication initiation is particularly important as it needs to be coordinated with other cellular events and should occur only once per cell cycle. Crucial players in the initiation of DNA replication are the...

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Bibliographic Details
Main Authors: Santiago Hernández-Pérez, Elisa Cabrera, Hugo Amoedo, Sara Rodríguez-Acebes, Stephane Koundrioukoff, Michelle Debatisse, Juan Méndez, Raimundo Freire
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Molecular Oncology
Subjects:
Initiation of DNA replication
DNA damage response
Ubiquitin hydrolase
DNA damage
Protein degradation
Proteasome
Online Access:https://doi.org/10.1016/j.molonc.2016.05.008

Internet

https://doi.org/10.1016/j.molonc.2016.05.008

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