Diet effects on colonic health influence the efficacy of Bin1 mAb immunotherapy for ulcerative colitis

Abstract Ulcerative colitis (UC) is an idiopathic disease of the large intestine linked to high fat-high protein diets, a dysbiotic microbiome, and a metabolome linked to diet and/or aberrant circadian rhythms associated with poor sleeping patterns. Understanding diet-affected factors that negativel...

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Bibliographic Details
Main Authors: Sunil Thomas, Nickey Dilbarov, Joseph Kelly, Giancarlo Mercogliano, George C. Prendergast
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38830-2