Novel peptides derived from αs1-casein with opioid activity and mucin stimulatory effect on HT29-MTX cells

Novel peptides derived from αs1-casein with opioid activity and mucin stimulatory effect on HT29-MTX cells

The opioid effect of αs1-casein fragments related to 143AYFYPEL149 and 144YFYPEL149, which had previously shown mucin-stimulatory activity in human goblet cells, was investigated. Peptides 144YFYPEL149 and 144YFYPE148 showed opioid agonistic activity in guinea pig ileum, and in mouse vas deferens bu...

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Bibliographic Details
Main Authors: S. Fernández-Tomé, D. Martínez-Maqueda, R. Girón, C. Goicoechea, B. Miralles, I. Recio
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Journal of Functional Foods
Subjects:
Opioid peptide
µ-Opioid receptor
Molecular dynamics
Mucin
Goblet cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616301669

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http://www.sciencedirect.com/science/article/pii/S1756464616301669

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