Novel peptides derived from αs1-casein with opioid activity and mucin stimulatory effect on HT29-MTX cells

Novel peptides derived from αs1-casein with opioid activity and mucin stimulatory effect on HT29-MTX cells

The opioid effect of αs1-casein fragments related to 143AYFYPEL149 and 144YFYPEL149, which had previously shown mucin-stimulatory activity in human goblet cells, was investigated. Peptides 144YFYPEL149 and 144YFYPE148 showed opioid agonistic activity in guinea pig ileum, and in mouse vas deferens bu...

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Bibliographic Details
Main Authors:	S. Fernández-Tomé, D. Martínez-Maqueda, R. Girón, C. Goicoechea, B. Miralles, I. Recio
Format:	Article
Language:	English
Published:	Elsevier 2016-08-01
Series:	Journal of Functional Foods
Subjects:	Opioid peptide µ-Opioid receptor Molecular dynamics Mucin Goblet cells
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464616301669

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