Western diet-induced obesity results in brain mitochondrial dysfunction in female Ossabaw swine

Western diet-induced obesity results in brain mitochondrial dysfunction in female Ossabaw swine

Diet-induced obesity is implicated in the development of a variety of neurodegenerative disorders. Concurrently, the loss of mitochondrial Complex I protein or function is emerging as a key phenotype across an array of neurodegenerative disorders. Therefore, the objective of this study was to determ...

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Bibliographic Details
Main Authors: Taylor J. Kelty, Chris L. Taylor, Nicole E. Wieschhaus, Pamela K. Thorne, Amira R. Amin, Christina M. Mueller, T. Dylan Olver, Darla L. Tharp, Craig A. Emter, Alexander W. Caulk, R. Scott Rector
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
obesity
mitochondrial dysfunction
Complex I syndrome
prefrontal cortex
hippocampus
Western diet
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1320879/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1320879/full

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