Outcomes in growth hormone-treated Noonan syndrome children: impact of PTPN11 mutation status

Outcomes in growth hormone-treated Noonan syndrome children: impact of PTPN11 mutation status

Introduction: Mutations in PTPN11 are associated with Noonan syndrome (NS). Although the effectiveness of growth hormone therapy (GHT) in treating sh ort stature due to NS has been previously demonstrated, the effect of PTPN11 mutation status on the long-term outcomes of GHT remains to be elucidated...

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Bibliographic Details
Main Authors: Alexander A L Jorge, Thomas Edouard, Mohamad Maghnie, Alberto Pietropoli, Nicky Kelepouris, Alicia Romano, Martin Zenker, Reiko Horikawa
Format: Article
Language:English
Published: Bioscientifica 2022-04-01
Series:Endocrine Connections
Subjects:
growth hormone
noonan syndrome
ptpn11
rasopathies
short stature
Online Access:https://ec.bioscientifica.com/view/journals/ec/aop/ec-21-0615/ec-21-0615.xml

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https://ec.bioscientifica.com/view/journals/ec/aop/ec-21-0615/ec-21-0615.xml

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