ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization

ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization

Abstract Background Anti-Silencing Factor 1 (ASF1) is a conserved H3–H4 histone chaperone involved in both Replication-Coupled and Replication-Independent (RI) nucleosome assembly pathways. At DNA replication forks, ASF1 plays an important role in regulating the supply of H3.1/2 and H4 to the CAF-1...

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Bibliographic Details
Main Authors: Béatrice Horard, Laure Sapey-Triomphe, Emilie Bonnefoy, Benjamin Loppin
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Epigenetics & Chromatin
Subjects:
ASF1
Histone chaperone
Drosophila
Early embryo
Pronucleus
Haploid
Online Access:http://link.springer.com/article/10.1186/s13072-018-0189-x

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http://link.springer.com/article/10.1186/s13072-018-0189-x

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