Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge.

Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge.

Show other versions (1)

The murine Bordetella pertussis challenge model has been utilized in preclinical research for decades. Currently, inconsistent methodologies are employed by researchers across the globe, making it difficult to compare findings. The objective of this work was to utilize the CD-1 mouse model with two...

Full description

Bibliographic Details
Main Authors: Kelly L Weaver, Graham J Bitzer, M Allison Wolf, Gage M Pyles, Megan A DeJong, Spencer R Dublin, Annalisa B Huckaby, Maria de la Paz Gutierrez, Jesse M Hall, Ting Y Wong, Matthew Warden, Jonathan E Petty, William T Witt, Casey Cunningham, Emel Sen-Kilic, F Heath Damron, Mariette Barbier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0286925&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0286925&type=printable

Similar Items