Sucralose Targets the Insulin Signaling Pathway in the SH-SY5Y Neuroblastoma Cell Line

Sucralose Targets the Insulin Signaling Pathway in the SH-SY5Y Neuroblastoma Cell Line

Sucralose is widely used as a non-nutritive sweetener (NNS). However, in order to justify its use as a non-nutritive food additive, sucralose would have to be metabolically neutral. The aim of this study was to examine whether sucralose altered the insulin signaling pathway in an in vitro cell model...

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Bibliographic Details
Main Authors: Marina Čović, Milorad Zjalić, Lovro Mihajlović, Marianna Pap, Jasenka Wagner, Dario Mandić, Željko Debeljak, Marija Heffer
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Metabolites
Subjects:
non-nutritive sweetener
insulin signaling
dopaminergic neurons
insulin like growth factor 1 receptor
neurodegeneration
Online Access:https://www.mdpi.com/2218-1989/13/7/817

Internet

https://www.mdpi.com/2218-1989/13/7/817

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