Establishment and Characterization of Brain Cancer Primary Cell Cultures From Patients to Enable Phenotypic Screening for New Drugs

Aim: Desmoplastic infantile ganglioglioma (DIG), is a rare tumor arising mainly during the first 2 years of life. Molecular characterization of these benign yet rapidly proliferating tumors has been limited to evaluating a few mutations in few genes. Our aim was to establish a live cell culture to e...

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Bibliographic Details
Main Authors: Michelle dePadua, Preethi Kulothungan, Rahul Lath, Ravikanti Prasad, Kranthi Madamchetty, Shravya Atmakuri, Sravanthi Ragamouni, Mukesh Gandhari, Lakshmipathi Khandrika, Jugnu Jain
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.778193/full