The novel bisphosphonate disodium dihydrogen-4-[(methylthio) phenylthio] methanebisphosphonate increases bone mass in post-ovariectomy rats

The novel bisphosphonate disodium dihydrogen-4-[(methylthio) phenylthio] methanebisphosphonate increases bone mass in post-ovariectomy rats

The novel bisphosphonate (BP) disodium dihydrogen-4-[(methylthio) phenylthio] methanebisphosphonate (MPMBP) is a non-nitrogen-containing BP with an antioxidant side chain that possesses anti-inflammatory properties. We investigated the systemic effects of this compound on bone loss induced by ovarie...

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Bibliographic Details
Main Authors: Aiko Takizawa, Mirei Chiba, Takeru Ota, Mayumi Yasuda, Keiko Suzuki, Takuya Kanemitsu, Takashi Itoh, Hisashi Shinoda, Kaoru Igarashi
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Pharmacological Sciences
Subjects:
Disodium dihydrogen-4-[(methylthio) phenylthio] methanebisphosphonate (MPMBP)
Anti-inflammatory
Ovariectomy
Bone formation
Bone resorption
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300275

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http://www.sciencedirect.com/science/article/pii/S1347861316300275

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