Increased pore size of scaffolds improves coating efficiency with sulfated hyaluronan and mineralization capacity of osteoblasts

Increased pore size of scaffolds improves coating efficiency with sulfated hyaluronan and mineralization capacity of osteoblasts

Abstract Background Delayed bone regeneration of fractures in osteoporosis patients or of critical-size bone defects after tumor resection are a major medical and socio-economic challenge. Therefore, the development of more effective and osteoinductive biomaterials is crucial. Methods We examined th...

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Bibliographic Details
Main Authors: Jan Krieghoff, Ann-Kristin Picke, Juliane Salbach-Hirsch, Sandra Rother, Christiane Heinemann, Ricardo Bernhardt, Christian Kascholke, Stephanie Möller, Martina Rauner, Matthias Schnabelrauch, Vera Hintze, Dieter Scharnweber, Michaela Schulz-Siegmund, Michael C. Hacker, Lorenz C. Hofbauer, Christine Hofbauer
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2019-12-01
Series:Biomaterials Research
Subjects:
Biomaterial
Macroporous scaffold
Mineralization
Osteoblast differentiation
Poly(lactic acid)
Sulfated glycosaminoglycan
Online Access:https://doi.org/10.1186/s40824-019-0172-z

Internet

https://doi.org/10.1186/s40824-019-0172-z

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