Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells

Summary: Tet2 is a member of the Ten-eleven translocation (Tet1/2/3) family of enzymes and is expressed in embryonic stem cells (ESCs). It demethylates DNA (catalytic functions) and partners with chromatin modifiers (noncatalytic functions) to regulate genes. However, the significance of these funct...

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Bibliographic Details
Main Authors: Julio C. Flores, Simone Sidoli, Meelad M. Dawlaty
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012476