CID fragmentation, H/D exchange and supermetallization of Barnase-Barstar complex

Abstract The barnase-barstar complex is one of the most stable protein-protein complexes and has a very wide range of possible applications. Here we report the use of top-down mass spectrometry for the investigation of the structure of this complex, its ionization via ESI, isolation and fragmentatio...

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Bibliographic Details
Main Authors: Yury Kostyukevich, Aleksej A. Shulga, Alexey Kononikhin, Igor Popov, Eugene Nikolaev, Sergey Deyev
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06507-2