Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy–Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells

Mitoxantrone-Loaded Nanoparticles for Magnetically Controlled Tumor Therapy–Induction of Tumor Cell Death, Release of Danger Signals and Activation of Immune Cells

Stimulating the patient’s immune system represents a promising therapeutic strategy to fight cancer. However, low immunogenicity of the tumor cells within an immune suppressive milieu often leads to weak anti-tumor immune responses. Additionally, the immune system may be impaired by accompanying agg...

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Bibliographic Details
Main Authors: Teresa Ratschker, Laura Egenberger, Magdalena Alev, Lisa Zschiesche, Julia Band, Eveline Schreiber, Benjamin Frey, Anja Derer, Christoph Alexiou, Christina Janko
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceutics
Subjects:
nanomedicine
iron oxide nanoparticles
chemotherapy
magnetic drug targeting
cell death
Online Access:https://www.mdpi.com/1999-4923/12/10/923

Internet

https://www.mdpi.com/1999-4923/12/10/923

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