Role of the mucin-like glycoprotein FCGBP in mucosal immunity and cancer

Role of the mucin-like glycoprotein FCGBP in mucosal immunity and cancer

IgGFc-binding protein (FCGBP) is a mucin first detected in the intestinal epithelium. It plays an important role in innate mucosal epithelial defense, tumor metastasis, and tumor immunity. FCGBP forms disulfide-linked heterodimers with mucin-2 and members of the trefoil factor family. These formed c...

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Bibliographic Details
Main Authors: Qiao Liu, Xia Niu, Yang Li, Jia-rui Zhang, Shao-jun Zhu, Qi-yuan Yang, Wei Zhang, Li Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
mucosal immunity
MUC2
FCGBP
TFF family
SARS-CoV-2
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.863317/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.863317/full

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