Autologous T-Cell-Free Antigen Presentation System Unveils hCMV-Specific NK Cell Response

NK cells play a decisive role in controlling hCMV infection by combining innate and adaptive-like immune reactions. The hCMV-derived VMAPRTLFL (LFL) peptide is a potent activator of NKG2C<sup>+</sup> NK cells. Proposed here is an autologous system of LFL stimulation without T lymphocytes...

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Bibliographic Details
Main Authors: Maria O. Ustiuzhanina, Maria A. Streltsova, Nikita D. Timofeev, Maxim A. Kryukov, Dmitriy M. Chudakov, Elena I. Kovalenko
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/6/530