Aggregation of platelets, proliferation of endothelial cells and motility of cancer cells are mediated by the Bβ1(15)-42 residue of fibrin(ogen)

Aggregation of platelets, proliferation of endothelial cells and motility of cancer cells are mediated by the Bβ1(15)-42 residue of fibrin(ogen)

The fibrinogen molecule contains multiple binding motifs for different types of cellular receptors, acting as a molecular link between coagulation and cell adhesion. In this study we generated a truncated form of the fibrinogen molecule lacking the Bβ1-42 sequence by site-specific proteolysis and ev...

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Bibliographic Details
Main Authors: Y. M. Stohnii, M. V. Ryzhykova, A. V. Rebriev, M. D. Kuchma, R. Y. Marunych, V. O. Chernyshenko, V. A. Shablii, N. M. Lypova, O. Yu. Slominskyi, L. V. Garmanchuk, T. M. Platonova, S. V. Komisarenko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2020-04-01
Series:The Ukrainian Biochemical Journal
Subjects:
adhesion
cell migration
cell proliferation
endothelium
fibrinogen
platelets
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2020/04/Stohnii_2_20.pdf

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http://ukrbiochemjournal.org/wp-content/uploads/2020/04/Stohnii_2_20.pdf

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