Hydrophobic gating in BK channels
BK channels are regulated by membrane voltage and intracellular Ca2+ but the structural features that block the ion flow in the closed state remain unknown. Here authors use molecular dynamics simulation and show that a physical gate is not required; instead ion flow is regulated by hydrophobic dewe...
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Nature Portfolio
2018-08-01
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| श्रृंखला: | Nature Communications |
| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41467-018-05970-3 |