Size exclusion chromatography as green support for forced degradation study of adalimumab

Size exclusion chromatography (SEC) has become a powerful tool for analysing size variants of biologic drugs in their native form. Modern SEC can be defined by the use of chromatographic columns packed with sub-3 µm particles, allowing an increase in method throughput compared to that of conventiona...

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Bibliographic Details
Main Authors: Kovačić Jelena, Klarić Daniela Amidžić, Turk Nikša, Mornar Ana
Format: Article
Language:English
Published: Sciendo 2023-12-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2023-0044