Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus)
Cuminum cyminum L., commonly known as cumin, which belongs to the family Apiaceae and the order Apiales, is a widely grown spice and medicinal plant in Xinjiang province, China. The fruit of cumin is primarily edible and is also consumed for its medicinal properties. However, after the cumin fruits...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-08-01
|
| Series: | Aquaculture Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513423002260 |
| _version_ | 1797752982689808384 |
|---|---|
| author | Hongyu Deng Zeyuan Tian Huiying Zhou Yongqiang Zhang Xinqiang Chen Yunwei Cui Abuduaini Aifeire Xi Zhang Zhixin Wei Peihong Shen Feiya Suo Luodong Huang |
| author_facet | Hongyu Deng Zeyuan Tian Huiying Zhou Yongqiang Zhang Xinqiang Chen Yunwei Cui Abuduaini Aifeire Xi Zhang Zhixin Wei Peihong Shen Feiya Suo Luodong Huang |
| author_sort | Hongyu Deng |
| collection | DOAJ |
| description | Cuminum cyminum L., commonly known as cumin, which belongs to the family Apiaceae and the order Apiales, is a widely grown spice and medicinal plant in Xinjiang province, China. The fruit of cumin is primarily edible and is also consumed for its medicinal properties. However, after the cumin fruits harvest, a large amount of plant stem waste is often produced, resulting in resource waste. In this study, fruits and stems of cumin were used at 1% and 3% concentrations (F1 and F3; S1 and S3, respectively) as feed additives to investigate the effects of their dietary supplementation on the growth, antioxidant capacity, liver, and intestinal health, and gut microbiota of Oreochromis niloticus. A total of 375 fish were fed, and their mean initial weight was 9.22 ± 0.17 g. After 8 weeks of feeding, the F1, S1, and S3 treatments significantly increased the weight gain rate and specific growth rate of O. niloticus. At the same time, S1 and S3 increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) and decreased the malondialdehyde (MDA) levels. S1 and S3 also reduced the activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the serum, reducing lipid droplet formation. Moreover, S1 and S3 significantly increased the length of intestinal villus and the abundance of Proteobacteria, reduced the abundance of Fusobacteriota and Bacteroidota in the gut, and increased the expression levels of metabolic pathways of the gut microbiome. The cumin stems and the fruits, at the lower 1% concentration, improved the growth performance of O. niloticus, accelerated growth rate, enhanced antioxidant capacity, improved intestinal morphology, and alleviated fatty liver disease. In particular, the stems of cumin have the potential to be used as feed additives for O. niloticus, providing a novel solution for the full utilization of agricultural waste. |
| first_indexed | 2024-03-12T17:11:19Z |
| format | Article |
| id | doaj.art-780fa246ce5e45fea8d2076f027890ae |
| institution | Directory Open Access Journal |
| issn | 2352-5134 |
| language | English |
| last_indexed | 2024-03-12T17:11:19Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aquaculture Reports |
| spelling | doaj.art-780fa246ce5e45fea8d2076f027890ae2023-08-06T04:37:45ZengElsevierAquaculture Reports2352-51342023-08-0131101687Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus)Hongyu Deng0Zeyuan Tian1Huiying Zhou2Yongqiang Zhang3Xinqiang Chen4Yunwei Cui5Abuduaini Aifeire6Xi Zhang7Zhixin Wei8Peihong Shen9Feiya Suo10Luodong Huang11College of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Xinjiang University, Urumchi 830046, ChinaResearch Insititute of Grain Crops, Xinjiang Academy of Agricultural Science, Urumchi 830091, ChinaCollege of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Xinjiang University, Urumchi 830046, ChinaCollege of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Guangxi University, Nanning 530004, ChinaCollege of Life Science and Technology, Xinjiang University, Urumchi 830046, China; Correspondence to: College of Life Science and Technology, Xinjiang University, No. 666 Shengli Road, Urumchi, Xinjiang 830046, China.College of Life Science and Technology, Guangxi University, Nanning 530004, China; Correspondence to: College of Life Science and Technology, Guangxi University, No.100 Daxue East Road, Nanning, Guangxi 530004, China.Cuminum cyminum L., commonly known as cumin, which belongs to the family Apiaceae and the order Apiales, is a widely grown spice and medicinal plant in Xinjiang province, China. The fruit of cumin is primarily edible and is also consumed for its medicinal properties. However, after the cumin fruits harvest, a large amount of plant stem waste is often produced, resulting in resource waste. In this study, fruits and stems of cumin were used at 1% and 3% concentrations (F1 and F3; S1 and S3, respectively) as feed additives to investigate the effects of their dietary supplementation on the growth, antioxidant capacity, liver, and intestinal health, and gut microbiota of Oreochromis niloticus. A total of 375 fish were fed, and their mean initial weight was 9.22 ± 0.17 g. After 8 weeks of feeding, the F1, S1, and S3 treatments significantly increased the weight gain rate and specific growth rate of O. niloticus. At the same time, S1 and S3 increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) and decreased the malondialdehyde (MDA) levels. S1 and S3 also reduced the activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the serum, reducing lipid droplet formation. Moreover, S1 and S3 significantly increased the length of intestinal villus and the abundance of Proteobacteria, reduced the abundance of Fusobacteriota and Bacteroidota in the gut, and increased the expression levels of metabolic pathways of the gut microbiome. The cumin stems and the fruits, at the lower 1% concentration, improved the growth performance of O. niloticus, accelerated growth rate, enhanced antioxidant capacity, improved intestinal morphology, and alleviated fatty liver disease. In particular, the stems of cumin have the potential to be used as feed additives for O. niloticus, providing a novel solution for the full utilization of agricultural waste.http://www.sciencedirect.com/science/article/pii/S2352513423002260Cuminum cyminumOreochromis niloticusLiver healthAntioxidant statusIntestinal microbe |
| spellingShingle | Hongyu Deng Zeyuan Tian Huiying Zhou Yongqiang Zhang Xinqiang Chen Yunwei Cui Abuduaini Aifeire Xi Zhang Zhixin Wei Peihong Shen Feiya Suo Luodong Huang Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus) Aquaculture Reports Cuminum cyminum Oreochromis niloticus Liver health Antioxidant status Intestinal microbe |
| title | Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus) |
| title_full | Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus) |
| title_fullStr | Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus) |
| title_full_unstemmed | Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus) |
| title_short | Elucidating the effects of cumin (Cuminum cyminum) fruit and stem as feed additives on growth, antioxidant capacity, liver and intestinal health, and gut microbiome of Nile tilapia (Oreochromis niloticus) |
| title_sort | elucidating the effects of cumin cuminum cyminum fruit and stem as feed additives on growth antioxidant capacity liver and intestinal health and gut microbiome of nile tilapia oreochromis niloticus |
| topic | Cuminum cyminum Oreochromis niloticus Liver health Antioxidant status Intestinal microbe |
| url | http://www.sciencedirect.com/science/article/pii/S2352513423002260 |
| work_keys_str_mv | AT hongyudeng elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT zeyuantian elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT huiyingzhou elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT yongqiangzhang elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT xinqiangchen elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT yunweicui elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT abuduainiaifeire elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT xizhang elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT zhixinwei elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT peihongshen elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT feiyasuo elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus AT luodonghuang elucidatingtheeffectsofcumincuminumcyminumfruitandstemasfeedadditivesongrowthantioxidantcapacityliverandintestinalhealthandgutmicrobiomeofniletilapiaoreochromisniloticus |